首页|Ex vivo liver resection and auto-transplantation as an alternative for the treatment of liver malignancies:Progress and challenges

Ex vivo liver resection and auto-transplantation as an alternative for the treatment of liver malignancies:Progress and challenges

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Hepatectomy is still the major curative treatment for patients with liver malignancies.However,it is still a big challenge to remove the tumors in the central posterior area,especially if their location involves the retrohepatic inferior vena cava and hepatic veins.Ex vivo liver resection and auto-transplantation(ELRA),a hybrid technique of the traditional liver resection and transplantation,has brought new hope to these patients and therefore becomes a valid alternative to liver transplantation.Due to its technical difficulty,ELRA is still concentrated in a few hepatobiliary centers that have experienced surgeons in both liver re-section and liver transplantation.The efficacy and safety of this technique has already been demonstrated in the treatment of benign liver diseases,especially in the advanced alveolar echinococcosis.Recently,the application of ELRA for liver malignances has gained more attention.However,standardization of clinical practice norms and international consensus are still lacking.The prognostic impact in these oncologic pa-tients also needs further evaluation.In this review,we summarized the principles and recent progresses on ELRA.

Ex vivo liver resectionLiver auto-transplantationOncologyLiver malignancies

Xin Yang、Lu Lu、Wen-Wei Zhu、Yi-Feng Tao、Cong-Huan Shen、Jin-Hong Chen、Zheng-Xin Wang、Lun-Xiu Qin

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Hepatobiliary Surgery and Liver Transplantation Centers,Department of General Surgery,Huashan Hospital & Cancer Metastasis Institute,Fudan University,Shanghai 200040,China

2024

国际肝胆胰疾病杂志(英文版)
浙江省医学学术交流管理中心,浙江大学医学院附属第一医院,浙江大学出版社有限责任公司

国际肝胆胰疾病杂志(英文版)

影响因子:0.668
ISSN:1499-3872
年,卷(期):2024.23(2)
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