首页|Solid pseudopapillary tumor of the pancreas:A systematic review of clinical,surgical and oncological characteristics of 1384 patients underwent pancreatic surgery

Solid pseudopapillary tumor of the pancreas:A systematic review of clinical,surgical and oncological characteristics of 1384 patients underwent pancreatic surgery

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  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
Background:Pancreatic solid pseudopapillary tumors(SPTs)are rare clinical entity,with low malignancy and still unclear pathogenesis.They account for less than 2％of exocrine pancreatic neoplasms.This study aimed to perform a systematic review of the main clinical,surgical and oncological characteristics of pancreatic SPTs.Data sources:MEDLINE/PubMed,Web of Science and Scopus databases were systematically searched for the main clinical,surgical and oncological characteristics of pancreatic SPTs up to April 2021,in accor-dance with the preferred reporting items for systematic reviews and meta-analyses(PRISMA)standards.Primary endpoints were to analyze treatments and oncological outcomes.Results:A total of 823 studies were recorded,86 studies underwent full-text reviews and 28 met in-clusion criteria.Overall,1384 patients underwent pancreatic surgery.Mean age was 30 years and 1181 patients(85.3％)were female.The most common clinical presentation was non-specific abdominal pain(52.6％of cases).Mean overall survival was 98.1％.Mean recurrence rate was 2.8％.Mean follow-up was 4.2 years.Conclusions:Pancreatic SPTs are rare,and predominantly affect young women with unclear pathogenesis.Radical resection is the gold standard of treatment achieving good oncological impact and a favorable prognosis in a yearly life-long follow-up.

Frantz's tumorPancreasPancreatic neoplasmsPancreatic surgerySolid pseudopapillary tumor

Gennaro Mazzarella、Edoardo Maria Muttillo、Diego Coletta、Biagio Picardi、Stefano Rossi、Simone Rossi Del Monte、Vito Gomes、Irnerio Angelo Muttillo

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Division of General and Emergency Surgery,San Filippo Neri Hospital,00136 Rome,Italy

Department of Surgery"Pietro Valdoni",Sapienza University of Rome,Viale del Policlinico 155,00161 Rome,Italy

Surgical and Medical Department of Translational Medicine,Sant'Andrea Hospital,Sapienza University of Rome,00185 Rome,Italy

Department of Surgical Sciences,Umberto I University Hospital,Sapienza University of Rome,00136 Rome,Italy

Department of General Surgery,Ospedali Riuniti Marche Nord,61121 Pesaro,Italy

Department of Pathology,San Filippo Neri Hospital,00136 Rome,Italy

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2024

10.1016/j.hbpd.2023.05.004

国际肝胆胰疾病杂志(英文版)
浙江省医学学术交流管理中心,浙江大学医学院附属第一医院,浙江大学出版社有限责任公司

国际肝胆胰疾病杂志(英文版)

影响因子：0.668
ISSN：1499-3872
年,卷(期)：2024.23(4)