首页|Red cell distribution width-to-albumin ratio is a simple promising prognostic marker in acute cholangitis requiring biliary drainage
Red cell distribution width-to-albumin ratio is a simple promising prognostic marker in acute cholangitis requiring biliary drainage
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国家科技期刊平台
NETL
NSTL
万方数据
Background:It is crucial to assess the severity of acute cholangitis(AC).There are currently several prog-nostic markers.However,the accuracies of these markers are not satisfied.The present study aimed to investigate the predictive value of the red cell distribution width(RDW)-to-albumin ratio(RAR)for the prognosis of AC.Methods:We retrospectively evaluated consecutive patients diagnosed with AC between May 2019 and March 2022.RAR was calculated,and its predictive ability for in-hospital mortality,intensive care unit(ICU)admission,bacteremia,and the length of hospitalization were analyzed.Results:Out of 438 patients,34(7.8％)died.Multivariate analysis showed that malignant etiology[odds ratio(OR)=4.816,95％confidence interval(CI):1.936-11.980],creatinine(OR=1.649,95％CI:1.095-2.484),and RAR(OR=2.064,95％CI:1.494-2.851)were independent risk factors for mortality.When ad-justed for relevant covariates,including age,sex,malignant etiology,Tokyo severity grading(TSG),Charl-son comorbidity index,and creatinine,RAR significantly predicted mortality(adjusted OR=1.833,95％CI:1.280-2.624).When the cut-off of RAR was set to 3.8,its sensitivity and specificity for mortality were 94.1％and 56.7％,respectively.Patients with an RAR of＞3.8 had a 20.9-fold(OR=20.9,95％CI:4.9-88.6)greater risk of mortality than the remaining patients.The area under the curve value of RAR for mortality was 0.835(95％CI:0.770-0.901),which was significantly higher than that of TSG and the other prognostic markers,such as C-reactive protein-to-albumin ratio,and procalcitonin-to-albumin ratio.Lastly,RAR was not inferior to TSG in predicting ICU admission,bacteremia,and the length of hospitalization.Conclusions:RAR successfully predicted the in-hospital mortality,ICU admission,bacteremia,and the length of hospitalization of patients with AC,especially in-hospital mortality.RAR is a promising marker that is more convenient than TSG and other prognostic markers for predicting the prognosis of patients with AC.
Acute cholangitisAlbuminBiliary drainageMortalityRed blood cell distribution width-to-albumin ratio
Fatih Acehan、Hüseyin Camli、Cagdas Kalkan、Mesut Tez、Burak Furkan Demir、Emin Altiparmak、Ihsan Ates
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Department of Internal Medicine,Ankara City Hospital,Ankara 06800,Türkiye
Department of Gastroenterology,Ankara City Hospital,Ankara 06800,Türkiye
Department of General Surgery,Ankara City Hospital,Ankara 06800,Türkiye
国家科技期刊平台
NSTL
万方数据
