首页|Displacement-pressure biparametrically regulated softness sensory system for intraocular pressure monitoring

Displacement-pressure biparametrically regulated softness sensory system for intraocular pressure monitoring

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High intraocular pressure(IOP)is one of the high-risk pathogenic factors of glaucoma.Existing methods of IOP measurement are based on the direct interaction with the cornea.Commercial ophthalmic tonometers based on snapshot measurements are expensive,bulky,and their operation requires trained personnel.Theranostic contact lenses are easy to use,but they may block vision and cause infection.Here,we report a sensory system for IOP assessment that uses a soft indentor with two asymmetrically deployed iontronic flexible pressure sensors to interact with the eyelid-eyeball in an eye-closed situation.Inspired by human fingertip assessment of softness,the sensory system extracts displacement-pressure information for soft evaluation,achieving high accuracy IOP monitoring(>96%).We further design and custom-make a portable and wearable ophthalmic tonometer based on the sensory system and demonstrate its high efficacy in IOP screening.This sensory system paves a way towards cost-effective,robust,and reliable IOP monitoring.

intraocular pressuretonometerdeep learningsoftnessiontronic sensor

Yu Cheng、Yifei Zhan、Fangyi Guan、Junli Shi、Jingxiao Wang、Yi Sun、Muhammad Zubair、Cunjiang Yu、Chuan Fei Guo

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Department of Materials Science and Engineering,Southern University of Science and Technology,Shenzhen 518055,China

Department of Engineering Science and Mechanics,Pennsylvania State University,State College 16802,USA

Department of Biomedical Engineering,Pennsylvania State University,State College 16802,USA

Department of Materials Science and Engineering,Materials Research Institute,Pennsylvania State University,State College 16802,USA

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National Natural Science Foundation of ChinaNational Natural Science Foundation of ChinaScience Technology and Innovation Committee of Shenzhen MunicipalityShenzhen Sci-Tech FundGuangdong Provincial Key Laboratory Program

T222501752 073 138JCYJ20210324120202007YTDPT201810111040072021B1212040001

2024

国家科学评论(英文版)

国家科学评论(英文版)

CSTPCD
ISSN:
年,卷(期):2024.11(6)