The virtual and real interactive robot entrepreneurship and innovation experimental class of Xiangtan University was established to explore the training mode of interdisciplinary integrated innovation and entrepreneurship practice talents.The experimental class of innovation and entrepreneurship education is created by introducing the mode of combining tutor guidance and students'self-management to provide students with an innovative environment.Students can be trained individually and broaden their horizons by the cooperation of different professional instructors to create a practical curriculum system with cutting-edge technology in all directions.Students'team spirit and team consciousness can be cultivated by cooperating with students of different majors to carry out innovative practice.A perfect individuality talent training model for interdisciplinary entrepreneurship and innovation experimental class has been gradually formed.A number of innovative and practical talents in the fields of intelligent manufacturing and control,machine vision,hardware circuit design,virtual instruments and other fields have been cultivated by the reform and exploration of this model,which has a certain reference value for the training of individuality talents training in interdisciplinary entrepreneurship and innovation experimental classes.