In the new stage of educational informatization,in order to explore more effective teaching methods and promote the cultivation of high-quality talents in communication engineering,the course Information Theory has carried out curriculum construction innovation and practice with the support of a number of provincial and school-level educational reform projects.In view of the problems existing in the course teaching process,the paper puts forward the teaching concept of"first-line trigger,ring propulsion,awaken thinking and activate kinetic energy"and the blended teaching mode of"three guides and three promotions driven by red gene in Xi'an University"of Electronic Seionce and Technology,and expounds the innovative methods and concrete implementation of teaching content,teaching organization,teaching methods and teaching evaluation.Teaching effect,teacher-student feedback,teaching achievements and promotion and application prove the effectiveness and demonstration of the teaching mode.