Cultivating top-notch innovative talents is a strategic focus of building a strong talent country in the new era.Due to the limitations of technological means,the traditional education model cannot effectively teach learners according to their learning needs,goals,and knowledge structure.Biochemistry is a cutting-edge discipline in the field of life sciences and an important foundational course in the field of medicine.This study is based on the construction project of high-quality online open courses in Biochemistry in Hunan Province,targeting medical students to explore and practice the reform of"digital intelligence"curriculum teaching mode.Through the application of artificial intelligence(AI+)technology,digital integration of teaching resources,visualization of intelligent teaching,personalization of learning models,and intelligent data processing are realized,which better mobilizes learners'learning motivation.Learners can flexibly and scientifically choose learning resources and methods based on their goals,achieving high efficiency,interesting,breadth,and depth in the study of Biochemistry course,and improving teaching effectiveness.