首页|Ptycho-endoscopy on a lensless ultrathin fiber bundle tip

Ptycho-endoscopy on a lensless ultrathin fiber bundle tip

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  • 国家科技期刊平台
  • NETL
  • NSTL
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Synthetic aperture radar(SAR)utilizes an aircraft-carried antenna to emit electromagnetic pulses and detect the returning echoes.As the aircraft travels across a designated area,it synthesizes a large virtual aperture to improve image resolution.Inspired by SAR,we introduce synthetic aperture ptycho-endoscopy(SAPE)for micro-endoscopic imaging beyond the diffraction limit.SAPE operates by hand-holding a lensless fiber bundle tip to record coherent diffraction patterns from specimens.The fiber cores at the distal tip modulate the diffracted wavefield within a confined area,emulating the role of the'airborne antenna'in SAR.The handheld operation introduces positional shifts to the tip,analogous to the aircraft's movement.These shifts facilitate the acquisition of a ptychogram and synthesize a large virtual aperture extending beyond the bundle's physical limit.We mitigate the influences of hand motion and fiber bending through a low-rank spatiotemporal decomposition of the bundle's modulation profile.Our tests demonstrate the ability to resolve a 548-nm linewidth on a resolution target.The achieved space-bandwidth product is～1.1 million effective pixels,representing a 36-fold increase compared to that of the original fiber bundle.Furthermore,SAPE's refocusing capability enables imaging over an extended depth of field exceeding 2 cm.The aperture synthesizing process in SAPE surpasses the diffraction limit set by the probe's maximum collection angle,opening new opportunities for both fiber-based and distal-chip endoscopy in applications such as medical diagnostics and industrial inspection.

Pengming Song、Ruihai Wang、Lars Loetgering、Jia Liu、Peter Vouras、Yujin Lee、Shaowei Jiang、Bin Feng、Andrew Maiden、Changhuei Yang、Guoan Zheng

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Department of Biomedical Engineering,University of Connecticut,Storrs,CT 06269,USA

CarlZeiss AG,Carl Zeiss Promenade,Jena,Thuringia 07745,Germany

United States Department of Defense,Washington,DC 20301,USA

School of Electrical and Electronic Engineering,Yonsei University,Seoul 03722,Republic of Korea

Department of Electronic and Electrical Engineering,University of Sheffield,Sheffield South Yorkshire S1 3JD,UK

Diamond Light Source,Harwell,Oxfordshire OX11 0DE,UK

Department of Electrical Engineering,California Institute of Technology,Pasadena,CA 91125,USA

Center for Biomedical and Bioengineering Innovation,University of Connecticut,Storrs,CT 06269,USA

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National Institute of HealthUConn SPARK grantNational Science FoundationNational Institute of HealthThermo Fisher Scientific fellowship

R01-EB0347442012140U01-NS113873

2024

10.1038/s41377-024-01510-5

光:科学与应用(英文版)
中国科学院长春光学精密机械与物理研究所

光:科学与应用(英文版)

CSTPCD
ISSN：2095-5545
年,卷(期)：2024.13(9)
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