摘要
目的：观察和评价中药根痛合剂治疗神经根型颈椎病疗效和安全性。方法100例神经根型颈椎病患者口服根痛合剂治疗，治疗前后测量患者血浆P物质（ SP）浓度并评定临床疗效。结果治疗两个疗程后，患者血浆SP浓度及疼痛评分均较治疗前明显降低（P＜0.01）；治疗效果：病程两个月以下显效率82.8％，病程两个月至一年显效率60％，病程一年以上显效率37.5％，总有效率为84.0％；治疗过程中无明显不良反应。结论根痛合剂治疗神经根型颈椎病的疗效明确、安全可靠，尤其适用于神经根型颈椎病急性期治疗。
Abstract
Objective To observe and assess efficacy and safety of Gengtong mixture in treating Cervical Spondylotic Radiculopathy . Methods Patients of Cervical Spondylotic Radiculopathy in 100 cases were given oral mixture treatment .We measured the plasma substance P(SP)level before and after the treatment , and evaluated the clinical efficacy .Results After two courses of treatment, plasma SP level and the pain score was significantly lower than before treatment ( P<0.01 ) .Efficacy: Effectual rate was 82.8% under two months , 60%two months to one year , 37.5%more than one year .Total effective rate was 84.0%.There was no significant adverse effects during the treatment.Conclusion Gengtong mixture treatment for Cervical Spondylotic Radiculopathy is effective , safe and reliable, which is especially suitable for acute phase of Cervical Spondylotic Radiculopathy .
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