Professor Zhu Hongjun has delved into the classics of traditional Chinese medicine(TCM)and accumulated abundant clinical experience,with unique insights into the treatment of coronary heart disease(CHD)with TCM.He believes that the lesion site of CHD is in the heart,but the symptoms come from the meridians,and cannot be separated from the circulation of spleen and stomach and the patency of Sanjiao.The pathogenesis of the disease is that insufficient qi and blood can easily lead to abnormal circulation of yin and other factors such as excessive fluid,which clumps together and enters the meridians after prolonged illness,ultimately leading to blockage and pain of the meridians.In terms of treatment,Professor Zhu holds that keeping"liquid circulation"well-regulated is the key to the treatment of CHD,and advocates that difficult diseases should be treated with"mixed therapy".Therefore,in clinical practice,he is good at regulating from the five aspects of qi,water,meridian,food(spleen and stomach),and Sanjiao.He summarized the diagnosis and treatment mode of"five channels co-therapy"in the treatment of CHD,and extracted the formula Qijin mini-pill from his experience,which has achieved significant therapeutic effects.This provides a new perspective and approach to the diagnosis and treatment of difficult diseases such as CHD based on the theory of TCM,which is worth promoting.