Using carboxymethyl cellulose sodium and polyethylene glycol as raw materials,a porous network structure was formed through cross-linking and gel,and a pH responsive gel membrane was prepared.The sam-ple obtained antibacterial properties by soaked in tannic acid solution,and the microstructure,swelling proper-ties,in vitro drug release,antioxidant properties,and antibacterial properties of the antibacterial membrane were characterized.The results show that the prepared antibacterial membrane has a good porous structure.The carboxyl group on carboxymethyl cellulose sodium endows the antibacterial membrane with certain pH respon-siveness,which makes it exhibit anisotropic swelling and drug release in vitro at different pH values.After drug loading,the antioxidant capacity of the sample increases to 91.33％,and the antibacterial rate against Esche-richia coli and Staphylococcus aureus reaches more than 90％.This antibacterial film has great application prospects in drug sustained-release dressings and other fields.
维普
万方数据