Bacterial infections and their drug resistance are one of the enormous health challenges in the world today,causing huge casualties and economic losses worldwide every year.Hydrogel is a three-dimensional poly-mer network structure colloid with good hydrophilicity,unique three-dimensional network,good biocompati-bility and cell adhesion.Therefore,hydrogel is a new type of biomaterial suitable for the antibacterial applica-tion and is expected to become a potential antibacterial material to solve antibiotic resistance.According to the corresponding antibacterial methods,the antibacterial technologies in hydrogels can be roughly classified into the following categories:(ⅰ)hydrogels loaded with antibacterial substances;(ⅱ)hydrogels with inherent anti-bacterial activity;(ⅲ)antibacterial hydrogels using photoresponsive therapy.This article will briefly introduce the basic principles,methods and applications of various hydrogel antibacterial technologies,and preliminarily discuss the difficulties and challenges in the future.
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