功能材料2024,Vol.55Issue(8) :8016-8020,8026.DOI:10.3969/j.issn.1001-9731.2024.08.003

钛表面钛酸钡纳米棒阵列构建及超声抗菌性能研究

Preparation and ultrasound-assisted antibacterial properties of barium titanate nanorod arrays on titanium

孙孟琳 张翔宇
功能材料2024,Vol.55Issue(8) :8016-8020,8026.DOI:10.3969/j.issn.1001-9731.2024.08.003

钛表面钛酸钡纳米棒阵列构建及超声抗菌性能研究

Preparation and ultrasound-assisted antibacterial properties of barium titanate nanorod arrays on titanium

孙孟琳 1张翔宇2
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作者信息

  • 1. 太原理工大学材料科学与工程学院,太原 030024
  • 2. 太原理工大学生物医学工程学院,太原 030024
  • 折叠

摘要

钛植入物术后细菌感染是临床上常见的并发症.通过水热处理和退火处理,在Ti表面构建了缺氧钛酸钡纳米棒(BaTiO3-x)阵列.采用扫描电子显微镜、透射电子显微镜、X射线衍射仪证实了 BaTiO3纳米棒的合成,采用X射线光电子能谱确认了氧空位的存在.以甲基紫(MV)为捕获剂验证了 BaTiO3-x纳米棒阵列在超声下的活性氧(ROS)产生能力.结果表明BaTiO3-x纳米棒阵列在超声波(US)辐照下可有效产生羟基自由基(·OH).抗菌实验表明,BaTiO3-x纳米棒阵列超声作用15 min对金黄色葡萄球菌(S.aureus)展现出优良抗菌能力,抗菌率达到90.92%.研究为钛植入体表面超声响应抗菌涂层的制备提供了思路.

Abstract

Postoperative bacterial infection of titanium implants is a common clinical complication.In this paper,arrays of oxygen-deficient barium titanate nanorods(BaTiO3-x)were constructed on the Ti surface by hydro-thermal and annealing treatments.The synthesis of BaTiO3 nanorods was confirmed using scanning electron mi-croscopy,transmission electron microscopy,and X-ray diffractometry,and the presence of oxygen vacancies was confirmed using X-ray photoelectron spectroscopy.The reactive oxygen species(ROS)generation ability of BaTiO3-x nanorod arrays under ultrasound was verified using methyl violet(MV)as a trapping agent.The re-sults show that BaTiO3-x nanorod arrays can effectively generate hydroxyl radicals(·OH)under ultrasonic(US)irradiation.Antibacterial experiments were conducted with Staphylococcus aureus(S.aureus),and the antibacterial capacity of BaTiO3-x nanorod arrays under US was investigated by the plate spread method.The results showed that the antibacterial rate of BaTiO3-x against S.aureus reached 90.92%after 15 min of US ir-radiation.This study provides ideas for the preparation of antimicrobial coatings on titanium implant surfaces and lays the foundation for expanding US-responsive antimicrobial coatings.

关键词

钛植入体/超声波/声动力/抗菌/纳米棒

Key words

titanium implants/ultrasound/sonodynamics/antibacterial/nanorod

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基金项目

国家自然科学基金项目(52171240)

出版年

2024
功能材料
重庆材料研究院 中国仪器仪表学会仪表材料学会

功能材料

CSTPCD北大核心
影响因子:0.918
ISSN:1001-9731
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