首页|婴幼儿护肤品中违禁激素丙酸氯倍他索的荧光渐变型比色分析

婴幼儿护肤品中违禁激素丙酸氯倍他索的荧光渐变型比色分析

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丙酸氯倍他索(CP)是一种糖皮质激素,可用于治疗湿疹、银屑病等皮肤病.婴幼儿长期频繁使用含CP的护肤品可能会导致严重的健康隐患.CP属化妆品禁添加组分,急需开发一种快速、简单护肤品中违禁激素CP的检测方法.通过橙色发光全无机钙钛矿量子点(CsPbBr1.5I1.5 QDs)和CP之间发生的卤素交换反应,荧光信号发生蓝移,偏移波长与CP浓度之间呈良好的线性关系,实现婴幼儿护肤品中CP含量的快速检测,检出限为0.2 mmol·L-1,检测时间为10 min.开发了用于婴幼儿护肤品中CP检测的荧光比色卡,可快速、准确、简便地用于婴幼儿护肤品中CP含量的检测.
Fluorescence Gradient Colorimetric Analysis of Clobetasol Propionate in Infant Skin Care Products
Clobetasol propionate(CP)is a kind of glucocorticoid,which can be used to treat eczema,psoriasis and other skin diseases.Long-term and frequent use of CP-contained skin care products by infants and young children may lead to serious health hazards.CP is a prohibited ingredient in cosmetics,and it is necessary to develop a rapid and simple method to detect the banned hormone CP in skin care products.In this work,there is a halogen exchange reaction between orange luminescent all-inorganic perovskite quantum dots(CsPbBr1.5I1.5 QDs)and CP,and the fluorescence peaks occur blue shift.There is an excellent linear relationship between the shift wavelength of CsPbBr1.5I1.5 QDs emission peak and the concentration of CP,which realizes the rapid analysis of the content of CP in infant skin care products.The detection limit is 0.2 mmol·L-1,and the detection time is 10 min.A luminescent color card for CP detection in infant skin care products was made,which could be used to quickly,accurately,and simply evaluate CP content in infant skin care products.

Fluorescence spectrumInfant skin care productsClobetasol propionateAll-inorganic perovskiteFluorescence colorimetric analysis

许春华、张惠煊、孙毓、唐楷臻、徐银娟、赵媛

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江南大学化学与材料工程学院,合成与生物胶体教育部重点实验室,江苏无锡 214122

荧光光谱 婴幼儿护肤品 丙酸氯倍他索 全无机钙钛矿量子点 荧光比色分析

国家自然科学基金

22278184

2024

光谱学与光谱分析
中国光学学会

光谱学与光谱分析

CSTPCD北大核心
影响因子:0.897
ISSN:1000-0593
年,卷(期):2024.44(6)
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