Advances in research on secondary metabolism and sporulation regulation mechanisms in Streptomyces
Streptomyces,widely distributed in nature,are known for their prolific production of various biologically active natural products,particularly antibiotics.Investigating the regulatory mechanisms of sporulation in Streptomyces is of significant importance for this applications.During the process of sporulation in Streptomyces,the morphological differentiation of hyphae is closely associated with the cell cycle.In this process,the cell skeleton and cell wall of Streptomyces are reorganized,and cell division and chromosome recombination occur during spore formation.Provides a comprehensive review of the reproductive process of Streptomyces and the key regulatory genes involved in sporulation.The includes the assembly of Z-rings,the formation of aerial hyphae and substrate mycelium,chromosome segregation in the pre-spore compartment of Streptomyces,and the formation of spore septa,while discussing the associated regulatory genes and proteins,to provide theoretical references for its applications in related fields.
Streptomyces spp.regulation of spore productionsecondary metabolitesspore
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