The Optimization of the Preparation of Chinese Medicine Formula Granules Based on Orthogonal Experiment
Objective:To explore the factors that affects the dosage of Chinese medicine formula granules,optimize the best dispensing and storage conditions,ensure the safety and effectiveness of the patients'medication,and improve the patients'satisfaction with Chinese medicine formula granules.Methods:The dispensing and storage conditions were optimized by orthogonal experiment,the quality of Chinese medicine formula granules were supervised,in order to obtain drugs of qualified quality.Results:The influencing factors of the preparation of Chinese medicine formula granules were humidity>the diameter of the granules>temperature;the best preparation technology was a temperature of 21℃,a humidity of 45%and the diameter of the granules could pass through the sieve No.2,and not through the sieve No.3.Conclusion:Temperature,humidity and the diameter of the granules have significant influence on the preparation of Chinese medicine formula granules,and the optimal dosing conditions obtained in the experiment could achieve the most accurate dosage.
Chinese medicine formula granulesorthogonal experimentdosagedispensing process