Objective:To provide the reference for the researchers'investigation into research current state and developmental trend of network pharmacology(NP)in TCM by analyzing the articles published,author distribution,institution distribution,keywords co-occurrence,keywords cluster and keywords emergency of NP in TCM.Methods:Knowledge map of NP in TCM was drawn using CiteSpace software,after searching NP-related literature in TCM from CNKI,between the time of building the database and February 28,2012.Results:The study has included 2 474 papers,application study on NP in TCM began from 2006,and the number of articles published soared since 2017,with the core authors were Zhang Tao,Li Jie,Zheng Jinghui and others,and the main research institutions contained Beijing University of Chinese Medicine and Liaoning University of Traditional Chinese Medicine,and the cooperation documents were mainly inside the institutions;research hot spots mainly focused on the mechanisms of treating COVID-19,type two diabetes mellitus(T2DM),coronary heart disease(CHD)by Huangqi(Astragali radix),Huanglian(Coptidis rhizoma),Danshen(Salviae miltiorrhizae radix et rhizoma)and ginseng.Conclusion:Visualized knowledge map of the main information of the literature could directly display research states of NP in TCM and developmental trend,and it could provide the reference for the researcher to quickly understand TCM.