Objective:To evaluate clinical effects of syndrome differentiation and treatment for vestibular migraine,and to explore the medication rules of TCM syndrome differentiation.Methods:A prospective cohort study of 197 patients with vestibular migraine was conducted,according to whether they accepted TCM syndrome differentiation and treatment as exposure factors,they were allocated to TCM group(123 cases)and Western medicine group(74 cases)respectively.To observe vertigo recurrence rate and the relevant outcome indicators after four,eight and 12 weeks of the treatment between both groups.Results:After four,eight and 12 weeks of the treatment,the relapse rates of vertigo in TCM groups were 14.9%,18.4%and 29.7%,while these in Western medicine group were 12.3%,32.8%and 55.6%,and the difference had statistical meaning after eight and 12 weeks of the treatment between both groups(P＜0.05);four weeks after the treatment,the improvements of DHI and VAS of the Western medicine group were better than these of TCM group,while the difference had no statistical meaning(P>0.05),the improvements of DHI and VAS of TCM group were superior to these of Western medicine group on the eighth and 12th weeks(P＜0.05);all 273 outpatient prescriptions were collected,involving 76 herbs,the top ten traditional Chinese medicine used were Tianma(Gastrodiae rhizoma),Fabanxia(Pinelliae rhizoma praeparatum),Chaihu((Bupleuri radix),Fushen(Poria cum Ligno Hospite),Yuanzhi(Polygalae radix),Fuling(Poria),Suanzaoren(Ziziphi spinosae semen),Duanlonggu(forged fossil fragments),Zhenzhumu(Margaritifera concha)and Huangqin(Scutellariae radix).Conclusion:The advantages of syndrome differentiation and treatment for vestibular migraine are obvious in improving the symptoms of vertigo and controlling the recurrence of vertigo,however,it is slower than the onset of action of Western medicine treatment.Soothing liver and relieving depression,tranquilization with heavy materials could be adopted as the main therapy,and the tranquilizing method should be used throughout the treatment.
vestibular migrainesyndrome differentiation and treatmentthe medication rulescohort study
维普
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