首页|基于数据挖掘探讨国医大师治疗胸痹心痛痰瘀互结证用药规律及经验

基于数据挖掘探讨国医大师治疗胸痹心痛痰瘀互结证用药规律及经验

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目的:探讨国医大师治疗胸痹心痛痰瘀互结证的用药规律及治疗经验.方法:以题目"胸痹心痛""胸痹""心痛""冠心病"并包含120位国医大师姓名,和/或作者中包含国医大师姓名为检索式,检索中国知网、维普、万方等数据库,整理筛选后纳入胸痹心痛痰瘀互结证相关文献,文献中涉及的处方经中医传承辅助平台V3.0统计分析,总结国医大师的用药规律及其经验.结果:胸痹心痛痰瘀互结证以胸闷、胸痛为主症,伴有气短、乏力、眠差等次症;舌象以舌暗红,苔白腻为主;脉象以脉弦滑和脉细为主;高频药物主要有丹参、川芎、瓜蒌等;药物功效使用频次最多的依次是活血化瘀类、补虚类、理气类、化痰止咳平喘类及清热类等;使用频次最多的3组药对分别为瓜蒌-薤白、丹参-瓜蒌、丹参-党参,3个核心组合中以川芎、丹参、黄芪、郁金、瓜蒌(核心组合2)出现频次最多.结论:国医大师治疗胸痹心痛痰瘀互结证以活血化瘀、补气化痰为主,常用血府逐瘀汤、丹参饮、瓜蒌薤白半夏汤、温胆汤等方剂化裁加减,随证治之.
TCM National Master's Medication Rules and Experience of the Treatment of Thoracic Obstruction and Cardiac Pain of Intermingled Phlegm and Blood Stasis Pattern Based on Data Mining
Objective:To investigate TCM national masters'medication rules and therapeutic experience in the treatment of thoracic obstruction and cardiac pain of intermingled phlegm and blood stasis pattern.Methods:The literature on thoracic obstruction and cardiac pain of intermingled phlegm and blood stasis pattern was searched from CNKI,CQVIP,Wanfang and other databases,with the titles of"thoracic obstruction and cardiac pain","thoracic obstruction""cardiac pain","coronary heart disease",including the names of 120 national masters of Chinese medicine,and/or the authors'names containing the names of the national masters of Chinese medicine as retrieval formula,and the papers were included after sorting and selecting,the prescriptions were analyzed statistically via traditional Chinese medicine inheritance support system(TCMISS V3.0)to summarize the national masters'medication rules and therapeutic experience.Results:Thoracic obstruction and cardiac pain of intermingled phlegm and blood stasis pattern is mainly characterized by chest tightness and chest pain,accompanied by shortness of breath,fatigue,poor sleep and other secondary symptoms,demonstrating dark red tongue and white and greasy tongue fur,slippery string and thin pulse;the high-frequency drugs mainly include Danshen(Salviae miltiorrhizae radix et rhizoma),Chuanxiong(Chuanxiong rhizoma)and Gualou(Trichosanthis fructus)and others;the statistical analysis of the efficacy of the drugs showed that the drugs with the highest frequency of use were the types of activating blood and removing blood stasis,tonifying deficiency,regulating Qi,resolving phlegm and relieving cough and asthma,clearing away heat;the association cluster analysis showed that three most frequent drug combinations were Gualou-Xiebai(Allii macrostemonis bulbus),Danshen-Gualou,Danshen-Dangshen(Codonopsis radix)respectively,and three core combinations,among them,Chuanxiong,Danshen,Huangqi(Astragali radix),Yujin(Curcumae radix)and Gualou appeared the most frequently.Conclusion:TCM national masters'treatment of thoracic obstruction and cardiac pain of intermingled phlegm and blood stasis pattern mainly adopts activating blood and removing blood stasis,tonifying Qi and resolving phlegm,the commonly-used prescription is Xuefu Zhuyu Tang,Danshen Yin,Gualou Xiebai Banxia Tang and Wendan Tang,modified in the application of the symptoms.

thoracic obstruction and cardiac painintermingled phlegm and blood stasiscoronary heart diseasedata miningTCM national master

朱若维、李雪菲、牛露娜、邓秘、郭惠怡、荆鲁

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中国中医科学院眼科医院,北京 100040

胸痹心痛 痰瘀互结证 冠心病 数据挖掘 国医大师

北京市中医药科技发展资金项目

JJ-2020-83

2024

西部中医药
甘肃中医药研究院

西部中医药

CSTPCD
影响因子:0.98
ISSN:1004-6852
年,卷(期):2024.37(3)
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