Clinical Observation on Dujieqing Oral Liquid and VAD Regimen in the Treatment of Multiple Myeloma
Objective:To observe clinical effects of Dujieqing oral liquid combined with VAD regimen(vincristine+doxorubicin+dexamethasone)in the treatment of multiple myeloma(MM).Methods:Clinical data of 82 MM patients admitted to the First Affiliated Hospital of Guangxi University of Chinese Medicine was retrospectively analyzed from March,2015 to March,2020,and they were allocated to 52 cases of the combination group and 30 cases of the control group in accordance with therapeutic regimen,the control group adopted VAD regimen,and the combination group was treated with Dujieqing oral liquid and VAD regimen.To compare clinical effects,the incidences of adverse reactions,TCM syndrome integrals,the indexes of renal function and lab indicators between both groups before and after the treatment.Results:The difference had no statistical meaning in clinical effects,total incidences of adverse reactions between both groups(P＞0.05);after the treatment,TCM syndrome integrals,the levels of Scr,BUN,monoclonal protein,β2-MG and LDH of the combination group were lower than those of the control group(P＜0.05),the levels of Hb higher than those of the control group(P＜0.05).Conclusion:Dujieqing oral liquid combined with VAD regimen could effectively alleviate the clinical symptoms of MM patients,improve the renal function,the levels of serum Hb,M protein,β2-MG and LDH with certain safety.
万方数据
维普
