首页|中医药靶向调控IL-6/JAK/STAT3通路的抗消化系统肿瘤研究进展

中医药靶向调控IL-6/JAK/STAT3通路的抗消化系统肿瘤研究进展

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就近年来白细胞介素6/非受体酪氨酸蛋白激酶/信号转导和转录激活因子3(interleukin-6/janus activated kinase/signal transducer and activator of transcription 3,IL-6/JAK/STAT3)信号通路在多种消化系统肿瘤中发挥的效应、中药单体及其活性成分、中药复方对与IL-6/JAK/STAT3信号通路调控有关的消化系统肿瘤中的防治作用进行综述,探究中医药在延缓、阻抑甚至逆转炎-癌转化中发挥的作用,为防治肿瘤提供更有力的理论指导.
Progress of Anti-gastrointestinal Tumor Research by Targeting and Regulating IL-6/JAK/STAT3 Pathway in Chinese Medicine
The paper reviewed the effects of interleukin-6/janus activated kinase/signal transducer and activator of transcription 3,IL-6/JAK/STAT3)signaling pathway in various digestive system tumors,the preventive and therapeutic effects of traditional Chinese medicine monomers and their active ingredients,and traditional Chinese medicine compounds on digestive system tumors related to the regulation of the IL-6/JAK/STAT3 signaling pathway in recent years.The role of traditional Chinese medicine in delaying,inhibiting,and even reversing inflammation-cancer transformation provides more powerful theoretical guidance for the prevention and treatment of tumors.

Chinese medicineinterleukin 6/janus activated kinase/vated protein kinase/signal transducer and activator of transcription 3 signaling pathwaydigestive system tumorsreview

李晓玲、吴玉泓、梁永林、李海龙

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甘肃中医药大学,甘肃 兰州 730000

深圳大学附属华南医院,广东 深圳 518111

中医药 白细胞介素6 非受体酪氨酸蛋白激酶 信号转导和转录激活因子3信号通路 消化系统肿瘤 综述

国家自然科学基金全国中医基础优秀人才研修项目(第四批)甘肃省中医药局项目

81860810J20184832009GZK-2018-5

2024

10.12174/j.issn.2096-9600.2024.06.23

西部中医药
甘肃中医药研究院

西部中医药

CSTPCD
影响因子：0.98
ISSN：1004-6852
年,卷(期)：2024.37(6)
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