Clinical Observation of Adjuvant Therapy of Severe Asthma Differentiated by TCM
Objective:To investigate the clinical efficacy of TCM syndrome differentiation and treatment combined with glucocorticoid inhalation in the treatment of severe asthma.Methods:Eighty-seven patients with severe asthma were selected and divided into the observation group(43 cases)and the control group(44 cases)by applying the method of randomized numerical table.The control group was given symptomatic treatment including routine anti-infection,bronchodilator,relieving cough and asthma.The observation group was divided into 11 cases in the stasis group,eight cases in the lung excess group and 12 cases in the cold-embracing fire group and 12 cases in the severe cold group according to the traditional Chinese medicine syndrome differentiation and patterns,combined with traditional Chinese medicine syndrome differentiation and treatment on the basis of the treatment of the control group,and the observation group was treated for one month in total.To compare the clinical efficacy of the two groups,the changes of lung function indexes,heart rate,breathing rate and oxygen saturation before and after treatment.Results:The total effective rate of the observation group was[90.70%(39/43)],higher than[72.73%(32/44)]of the control group(P<0.05);the difference had no statistical meaning in the comparisons of total effective rates between the stasis group,lung excess group,cold-embracing fire group and the severe cold group(P<0.05);after the treatment,diffusion capacity of lung carbon monoxide,the residual volume to the total lung volume ratio,forced expiratory volume in the first second to forced vital capacity ratio of the observation group were significantly better than those of the control group(P<0.05);heart rate and respiratory rate improved in both groups after treatment,but the difference was not statistically significant(P>0.05);blood oxygen saturation increased in both groups,and the observation group was higher than the control group(P<0.05).Conclusion:The treatment of severe asthma with TCM syndrome differentiation and treatment combined with inhaled glucocorticoid method can enhance the therapeutic effect,and it has significant effect on patients with severe asthma of different patterns,and it can enhance the lung function and oxygen saturation of patients.
asthma,severeTCM syndrome differentiationglucocorticoidlung function
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