摘要
中医学认为紫癜性肾炎是过敏性紫癜出现肾脏损害时的表现,病因主要有风、热、湿、毒、瘀、虚等,治疗以清热、祛瘀、补虚为主,并进一步提出从血分论治紫癜性肾炎.急性期宜凉血散血,缓解期宜活血化瘀,恢复期宜养血补血,进而探讨中医药从血分论治紫癜性肾炎的分子机制.
Abstract
In traditional Chinese medicine,Henoch-Schonlein purpura nephritis(HSPN)is the manifesta-tions of Henoch-Schonlein purpura(HSP)when the renal damage occurs,and its causes mainly contain wind,heat,dampness,toxin,stasis and deficiency,the treatment covers clearing heat,eliminating stasis and tonifying the deficiency.We further propose to treat HSPN from the aspect of blood,adopt cooling blood and dispelling blood at the acute stage,promoting blood circulation to removing blood stasis at the remission stage,nourishing blood and tonifying blood at the rehabilitation stage,and discuss the molecular mechanism of TCM treatment of HSPN from the aspect of blood.
基金项目
国家自然科学基金地区基金(82060849)
国家自然科学基金青年基金(81704052)
江西省自然科学基金(20171BAB215055)
江西省教育厅科学技术研究项目(160850)