Objective:To analyze the acupoint selection rules for acupuncture treatment of anal pain after the surgery of mixed hemorrhoids based on data mining.Methods:The literature on acupuncture therapy for posto-perative pain of mixed hemorrhoids were searched from China Journal Full-Text Database(CJFD),Wanfang,VIP between April 20,2003 and September 24,2020,involving 419 papers.SPSS 26.0 and SPSS modeler 18.0 soft-ware were applied to conduct statistical analysis of the acupoint selection rules for acupuncture treatment of anal pain.Results:The acupoints for acupuncture therapy of anal pain after the surgery of mixed hemorrhoids ranked in the descending order:Chengshan(BL57),Changqiang(DU1),Erbai(EX-UE2),Ciliao(BL28),Baihuanshu(BL30),Xialiao(BL34),Zhongliao(BL33),Zusanli(ST36),Shangliao(BL31);belonging to bladder meridian,conception channel,spleen meridian and governor meridian mainly;the acupoints were chosen from lumbosacral region and lower extremities the most;the commonly-used special acupoints were Luo-connecting points and extra nerve points.Conclusion:The acupoint selection rules for acupuncture treatment of anal pain after the surgery of mixed hemorrhoids are analyzed based on the method of data mining,and the acupoints are selected from lumbosacral region and four extremities,conforming to clinical therapeutic laws.