首页|肠道微生物诱导胆囊结石形成机制的研究进展

肠道微生物诱导胆囊结石形成机制的研究进展

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研究证实肠道微生物通过多种途径参与胆囊结石的发生、发展,湿热证是胆囊结石的中医病机,而肠道微生物与湿热证相互作用,相互影响.文章从肠道微生物及其代谢产物通过调控胆汁酸代谢及中医湿热内蕴引起肠道微生物失衡而诱发胆囊结石等方面阐述肠道微生物引起胆囊结石的发生机制,并指出调整肠道微生物及其代谢产物可能是预防和治疗胆囊结石的新的治疗方向.
Research Progress of the Mechanism of Gallbladder Calculus Formation Induced by Gut Microorganisms
More and more research has confirmed that gut microorganisms are involved in the occurrence and development of gallbladder stones,interacting with the damp-heat pattern,as damp-heat pattern is the pathogenesis of gallbladder stones in TCM.The mechanism of gallbladder stone formation induced by intestinal microorganisms was elaborated from the aspects that intestinal microorganisms and their metabolites regulate the metabolism of bile acids,and the imbalance of intestinal microorganisms caused by the internal accumulation of damp-heat,thereby inducing gallbladder stones,meanwhile,the regulation of intestinal microorganisms and their metabolites might be the new therapeutic direction for the prevention and treatment of gallbladder calculus.

gallbladder calculusgut microorganismsbile aciddamp-heat patternthe mechanism

潘浩宇、刘志春、张春花、王定新

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甘肃中医药大学第一临床医学院,甘肃 兰州 730000

天水市第一人民医院,甘肃 天水 741000

天水市卫生健康委员会,甘肃 天水 741000

胆囊结石 肠道微生物 胆汁酸 湿热证 机制

2024

西部中医药
甘肃中医药研究院

西部中医药

CSTPCD
影响因子:0.98
ISSN:1004-6852
年,卷(期):2024.37(12)