Research Progress of the Mechanism of Gallbladder Calculus Formation Induced by Gut Microorganisms
More and more research has confirmed that gut microorganisms are involved in the occurrence and development of gallbladder stones,interacting with the damp-heat pattern,as damp-heat pattern is the pathogenesis of gallbladder stones in TCM.The mechanism of gallbladder stone formation induced by intestinal microorganisms was elaborated from the aspects that intestinal microorganisms and their metabolites regulate the metabolism of bile acids,and the imbalance of intestinal microorganisms caused by the internal accumulation of damp-heat,thereby inducing gallbladder stones,meanwhile,the regulation of intestinal microorganisms and their metabolites might be the new therapeutic direction for the prevention and treatment of gallbladder calculus.