Effects of Nodulus-eliminating Pain-relieving Capsules Combined with Dienogest on Serum EMAb and CA125 in Patients with Endometriosis
Objective:To observe clinical effects of Sanjie Zhentong capsules(nodulus-eliminating pain-reliev-ing capsules)joined with dienogest in the treatment of endometriosis and its influence on the levels of anti-endometrial antibody(EMAb)and carbohydrate antigen(CA125).Methods:Sixty patients were chosen and randomized into the observation group and the control group,30 cases in each group.The observation group was treated with nodulus-eliminating pain-relieving capsules and dienogest,and dienogest was administered to the control group.All the patients were treated for six menstrual cycles.To compare VAS scores,the conversion rate of serum EMAb and the levels of serum CA125 before and after the treatment in the two groups,to assess clinical effects between both groups.Results:After the treatment,total effective rate of the observation group was[90.00%(27/30)],higher than[66.67%(20/30)]of the control group(P<0.05);the conversion rate of EMAb of the observa-tion group was[76.67%(23/30)],higher than[46.67%(14/30)]of the control group(P<0.05).After the treatment,VAS scores and the levels of serum CA125 were lower in the two groups than before the treatment(P<0.05),and the decrease of the observation group was greater than that of the control group(P<0.05).Conclusion:Nodulus-eliminating pain-relieving capsules and dienogest could obtain noticeable clinical effects in the treatment of endometriosis,which could effectively reduce the levels of CA125,increase EMAb conversiun rate without severe adverse reactions.
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