首页|补肾化浊颗粒对慢性肾衰竭血透患者的疗效观察

补肾化浊颗粒对慢性肾衰竭血透患者的疗效观察

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目的 探讨补肾化浊颗粒对慢性肾衰竭(CRF)血透患者的治疗效果。方法 选取医院2021年5月至2022年10月收治的89例CRF血透患者,根据患者入院单尾号分组,奇数纳对照组(45例)、偶数纳观察组(44例);对照组行常规治疗,观察组加用补肾化浊颗粒治疗;对比两组疗效、免疫功能指标(T淋巴细胞亚群CD3+、CD4+、CD8+)、肾功能指标[血肌酐(Scr)、血尿素氮(BUN)]及不良反应。结果 观察组总有效率较对照组高,差异有统计学意义(P<0。05);治疗4周,观察组CD3+、CD4+、CD8+水平较对照组高,Scr、BUN水平较对照组低,差异有统计学意义(P<0。05);两组不良反应发生率对比,差异无统计学意义(P>0。05)。结论 CRF血透患者采用补肾化浊颗粒治疗效果较好,可提高免疫功能,改善肾功能,且安全性好。
Observation of Curative Effect of Bushen Huazhuo Granules on Hemodialysis Patients with Chronic Renal Failure
OBJECTIVE To investigate the therapeutic effect of Bushen Huazhuo granules on hemodialysis patients with chronic renal failure(CRF).METHODS A total of 89 patients with CRF hemodialysis admitted to the hospital from May 2021 to October 2022 were divided into two groups according to the single tail number of patients admitted to the hospital:odd tolerance control group(45 cases)and even tolerance observation group(44 cases).The control group received conventional treatment,and the observation group was treated with Bushen Huazhuo granules.Efficacy,immune function indexes(T lymphocyte subsets CD3+、CD4+、CD8+),renal function indexes[blood creatinine(Scr),blood urea nitrogen(BUN)]and adverse reactions were compared between the two groups.RESULTS The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).After 4 weeks of treatment,the levels of CD3+,CD4+,and CD8+in the observation group were higher than those in the control group,and the levels of Scr and BUN were lower than those in the control group,the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).CONCLUSION Bushen Huazhuo granules can improve immune function and renal function with good safety in patients with CRF hemodialysis,which show good therapeutic effect.

chronic renal failureBushen Huazhuo granuleshemodialysisimmune functionrenal function

余国平、陈熙鸣、舒慧、曾琴、韩亚男、翁俊影

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江西省乐平市中医医院,江西景德镇 333300

全国基层名老中医药专家陈熙鸣工作室,江西景德镇 333300

慢性肾衰竭 补肾化浊颗粒 血液透析 免疫功能 肾功能

2024

今日药学
广东省药学会 中国药学会

今日药学

影响因子:0.413
ISSN:1674-229X
年,卷(期):2024.34(2)
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