Research Progress on the Immunogenic Cell Death and the Treatment of Breast Cancer
Immunog enic cell death(ICD)is a special form of cell death,which plays an important role in the treatment of breast cancer.Research shows that when specific chemotherapy drugs,radiotherapy or targeted drugs are used to treat breast cancer,tumor cells will release or increase the expression of damage associated molecular patterns(DAMPs),activate ICD,thereby improving the immunogenicity of tumor cells,recruiting and activating immune cells,and further stimulate or enhance anti-tumor immune response.This article summarizes the relevant preclinical studies on the use of induced ICD in the treatment of breast cancer,and provides a reference for the design of breast cancer therapy in the future.