Effects of early pulmonary rehabilitation based on Baduanjin on airway inflammation and prognosis in patients with AECOPD
Objective To investigate the effect of early pulmonary rehabilitation based on Baduanjin on airway inflammation and prognosis in patients with acute exacerbations of chronic obstructive pulmonary disease(AECOPD).Methods From May 2021 to June 2022,113 patients with AECOPD who met the inclusion criteria in Third Division in Internal Medicine Department of Panyu Hospital of Traditional Chinese Medicine in Guangzhou were selected and divided into pulmonary rehabilitation(PR)group(n=54)and control group(n=59)by random number table method.On the basis of basic treatment,the pulmonary rehabilitation group combined with the step type early pulmonary rehabilitation therapy with bullseye rate and the minimum blood oxygen saturation during exercise as safety control indexes,based on standing or lying position Baduanjin,combined with different intensity muscle strength training/treadmill training/step training as content.According to the dyspnea,fatigue score and exercise ability assessment,the pulmonary rehabilitation group was divided into an upright PR group of 29 cases and a supine PR group of 25 cases,and corresponding rehabilitation programs were given.The serum inflammatory indicators,pulmonary function,subjective assessment,self-care ability score,the number of re-acute exacerbations and all-cause mortality during the follow-up period were compared at different time points in the follow-up period,and the differences between groups and within rehabilitation subgroups including upright PR group and supine PR group were compared.Results Compared with the control group,the inflammation index CRP data measured at 7 days and 12 weeks after recovery in PR group were lower(P<0.05),and the SAA value had no statistical significance(P>0.05).The measured value of PaCO2 at 7 days after recovery was lower in PR group(P<0.05),and there was no significant difference in oxygenation index and FEV1%predicted(P>0.05).The median Borg dyspnea and fatigue scores were lower in PR group after 12 weeks of rehabilitation(P<0.01).The median score of self-care ability was higher in PR group after 12 weeks of rehabilitation(P<0.01);the number of acute exacerbations in PR group was less in the follow-up period(P<0.05).In subgroup analysis,the median difference of Borg dyspnea,fatigue score and self-care ability score in the decubitus group was greater after 12 weeks of rehabilitation(P<0.01),and there was no significant difference in inflammation index(P>0.05)and the number of acute exacerbations during follow-up(P>0.05).Conclusions Early pulmonary rehabilitation based on Baduanjin can reduce the inflammatory reaction of patients with AECOPD,improves carbon dioxide retention,improve subjective dyspnea and fatigue,enhance self-care ability,reduce the incidence of acute exacerbation events during follow-up,and improve the prognosis.The benefit is more obvious in the case group with worse baseline status.
Baduanjinearly pulmonary rehabilitationAECOPDquality of lifethe prognosis
万方数据
维普
