ed:Objective To study the differences in the constituents of Xiao'er Zhike Tangjiang between different enterprises by solvent peaks suppression and OPLS-DA analysis,and carry out effective differentiation and identification.Methods After segmenting and integrating the hydrogen spectra of 34 samples from 21 production batches from 6 enterprises,OPLS-DA method was used to analyze the spectra.Results The H spectra of Xiao'er Zhike Tangjiang from the six enterprises were similar,however the little contents were different after solvent peaks suppression.The results of two experiments were analyzed by OPLS-DA method,which indicated that the contents were different among different manufacturers.Conclusion An effective method could distinguish Xiao'er Zhike Tangjiang from different manufacturers by 1H-NMR fingerprint and OPLS-DA analysis,which provides a new method for the quality standard of Xiao'er Zhike Tangjiang.
关键词
小儿止咳糖浆/成分差异/溶剂峰压制/OPLS-DA识别模式
Key words
Xiao'er Zhike Tangjiang/the differences of constituents/solvent peaks suppression/orthogonal partial least squares analysis