Effect of miRNA on the occurrence and development of mental diseases and its diagnostic application prospects
MicroRNAs (miRNAs) are a class of non-coding single stranded RNA molecules encoded by endogenous genes,which affect a variety of biological transmission pathways through post-transcriptional regulation of gene expression. In recent years,a large number of studies have shown that patients with mental disorders exhibit abnormal expression of miRNAs compared to normal individuals. The research results suggest that microRNAs may be biomarkers for this type of disease. Therefore,searching and identifying miRNA target genes related to mental diseases is of great significance for understanding and diagnosing diseases. This article aims to elucidate how miRNAs regulate the central nervous system and the pathogenesis of mental disorders,and to provide a review of the application prospects of microRNAs in the diagnosis of mental disorders based on existing research results both domestically and internationally.
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