Atherosclerosis(AS)is a chronic inflammatory disease in the blood vessel wall,which is the main pathological basis of coronary heart disease,cerebral infarction and peripheral vascular disease.As the leading cell type in atherosclerotic plaques,vascular smooth muscle cells(VSMCs)play an important role in AS progression.This paper will explain the latest progress of the transformation of VSMCs on atherosclerosis,and provide a reliable theoretical basis for the treatment and research of AS.
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