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精神分裂症的病理机制及治疗方法进展

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精神分裂症作为常见于青壮年的精神疾病,病因不明,临床症状包括认知、情感、行为等多方面障碍.该病预后差、治疗负担重,对患者、家庭和社会都造成了一定影响.基于此类情况,本文介绍了精神分裂症的临床特征,围绕基因表达、神经递质、神经发育、炎症水平等方面汇总了对该病病理机制的认识,并对抗精神病药物、中药方剂、针刺疗法、神经调控技术、益生菌疗法治疗该病的相关研究进行综述,为后续深入研究提供参考.
Progress in pathological mechanisms and treatment methods of schizophrenia
As a common mental illness among young adults,schizophrenia(SZ)has an unknown etiology and clinical symptoms including cognitive,emotional,behavioral and other disorders.SZ has a poor prognosis and a large treatment burden,which has a certain impact on patients,families and society.Based on this situation,this article introduces the clinical characteristics of SZ,summarizes the understanding of the pathological mechanism of SZ around gene expression,neurotransmitters,neurodevelopment,inflammation levels,etc.,and reviews the relevant research on antipsychotic drugs,traditional Chinese medicine formulas,acupuncture therapy,neuromodulation technology,and probiotic therapy for the treatment of SZ,providing reference for further in depth research.

schizophreniapathological-mechanismstreatmenttraditional Chinese medicine

吴旻熹、洪语欣、黄夏仪、王韵瑶、黄深明、赵昌林、万超凡

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广东药科大学健康学院,广东 广州 510006

精神分裂症 病理机制 治疗 中医药

2024

广东药科大学学报
广东药学院

广东药科大学学报

CSTPCD
影响因子:0.698
ISSN:1006-8783
年,卷(期):2024.40(6)