广东药科大学学报2024,Vol.40Issue(6) :136-143.DOI:10.16809/j.cnki.2096-3653.2024040803

精神分裂症的病理机制及治疗方法进展

Progress in pathological mechanisms and treatment methods of schizophrenia

吴旻熹 洪语欣 黄夏仪 王韵瑶 黄深明 赵昌林 万超凡
广东药科大学学报2024,Vol.40Issue(6) :136-143.DOI:10.16809/j.cnki.2096-3653.2024040803

精神分裂症的病理机制及治疗方法进展

Progress in pathological mechanisms and treatment methods of schizophrenia

吴旻熹 1洪语欣 1黄夏仪 1王韵瑶 1黄深明 1赵昌林 1万超凡1
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作者信息

  • 1. 广东药科大学健康学院,广东 广州 510006
  • 折叠

摘要

精神分裂症作为常见于青壮年的精神疾病,病因不明,临床症状包括认知、情感、行为等多方面障碍.该病预后差、治疗负担重,对患者、家庭和社会都造成了一定影响.基于此类情况,本文介绍了精神分裂症的临床特征,围绕基因表达、神经递质、神经发育、炎症水平等方面汇总了对该病病理机制的认识,并对抗精神病药物、中药方剂、针刺疗法、神经调控技术、益生菌疗法治疗该病的相关研究进行综述,为后续深入研究提供参考.

Abstract

As a common mental illness among young adults,schizophrenia(SZ)has an unknown etiology and clinical symptoms including cognitive,emotional,behavioral and other disorders.SZ has a poor prognosis and a large treatment burden,which has a certain impact on patients,families and society.Based on this situation,this article introduces the clinical characteristics of SZ,summarizes the understanding of the pathological mechanism of SZ around gene expression,neurotransmitters,neurodevelopment,inflammation levels,etc.,and reviews the relevant research on antipsychotic drugs,traditional Chinese medicine formulas,acupuncture therapy,neuromodulation technology,and probiotic therapy for the treatment of SZ,providing reference for further in depth research.

关键词

精神分裂症/病理机制/治疗/中医药

Key words

schizophrenia/pathological-mechanisms/treatment/traditional Chinese medicine

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出版年

2024
广东药科大学学报
广东药学院

广东药科大学学报

CSTPCD
影响因子:0.698
ISSN:1006-8783
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