Preliminary study of active tuberculosis infections in maintenance hemodialysis patients
Objective To investigate the clinical characteristics and distribution of patients with active tuberculo-sis infection undergoing maintenance hemodialysis(MHD)in Guizhou Province,and provide clinical evidence for tu-berculosis prevention and control in hemodialysis patients.Methods A retrospective study was conducted using pa-tients with MHD of active tuberculosis infection who were treated at the Guiyang Public Health Treatment Center from January 2018 to December 2021.Patients were grouped according to whether they had undergone maintenance hemodialysis before diagnosis of active tuberculosis infection that the MHD TB infection group and the Pre-MHD TB infection group.Clinical data were collected and statistically analyzed.Result A total of 121 patients with MHD were selected,including 60 patients in the MHD TB infection group and 61 patients in the Pre-MHD TB infection group,mainly distributed in Guiyang City and Bijie region.Both groups were commonly affected by secondary pul-monary tuberculosis(83.60％VS.90.00％),with extrapulmonary tuberculosis accompanied by serous cavity tu-berculosis(31.10％VS.26.70％).However,there were no statistically significant differences between the two groups(P＞0.05).At the same time,47 patients(38.80％)had more than two sites of tuberculosis infection.The Pre-MHD TB infection group had a higher proportion of patients with fatigue and poor appetite as the initial symp-toms compared to the MHD TB infection group(23.00％VS.6.70％,P＜0.05),and more cases of extra-pulmo-nary tuberculosis occur in the urinary system.There were statistically significant differences between groups(P＜0.05).In the MHD TB infection group,15 patients(25.00％)were first diagnosed with abnormal chest CT examination,especially MHD patients with diabetes,and the comparison between the two groups was statistically significant(P＜0.05).Conclusion The clinical symptoms of patients with diabetic MHD and Pre-MHD TB infection lack speci-ficity,so individualized monitoring,strengthen screening and improved diagnostic efficiency are needed to decrease the risk of exposure and cross-infection for these patients.
Maintenance hemodialysisChronic kidney disease stage 5Tuberculosis infectionTuberculosis pre-vention and control
万方数据
维普
