首页|脑微出血对卒中防治策略的影响研究进展

脑微出血对卒中防治策略的影响研究进展

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微出血(cerebral microbleeds,CMBs)作为脑小血管病的重要表征,与缺血性脑卒中、出血性卒中、认知障碍和步态障碍等多种临床结局密切相关。在本综述中,我们概述了 CMBs介导的临床症状,评估CMBs是否会影响缺血性和出血性卒中的结局,以及其对卒中防治策略的影响。我们研究发现,CMBs的负荷和分布可显著影响卒中患者的发病风险、治疗预后及功能恢复。且在静脉溶栓、抗血小板和抗凝的治疗中,CMBs的存在与再灌注治疗后脑出血的风险密切相关。探索早期检测CMBs和个体化治疗方案,可优化卒中患者的治疗效果并降低相关风险。
Research progress on the impact of cerebral microbleeds on stroke prevention and treatment strategies
Cerebral microbleeds(CMBs),as an important manifestation of cerebral small vessel disease,are closely related to various clinical outcomes such as ischemic stroke,hemorrhagic stroke,cognitive impairment,and gait disorders.In this review,we outline the clinical symptoms mediated by CMBs,evaluate whether CMBs affect the outcomes of ischemic and hemorrhagic strokes,and their impact on stroke prevention and treatment strategies.Our research findings show that the burden and distribution of CMBs can significantly affect the risk of onset,treat-ment prognosis,and functional recovery in stroke patients.Moreover,in the treatments of intravenous thrombolys-is,antiplatelet,and anticoagulation,the presence of CMBs is closely related to the risk of cerebral hemorrhage after reperfusion therapy.Exploring early detection of CMBs and individualized treatment regimens can optimize the treatment effect and reduce related risks in stroke patients.

Cerebral microbleedsClinical symptomsStrokeTreatmentPrognosis

陈东亚、胡哲淇、柯志鸿、毛程璐、徐运

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江苏大学鼓楼临床医学院神经内科,江苏南京 210008

南京大学医学院附属鼓楼医院神经内科,江苏南京 210008

南京医科大学附属鼓楼临床医学院,江苏南京 210008

脑微出血 临床症状 脑卒中 治疗 预后

2025

贵州医药
贵州省医药卫生学会办公室

贵州医药

影响因子:0.493
ISSN:1000-744X
年,卷(期):2025.49(1)