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不明原因复发性流产免疫稳态平衡及治疗的研究进展

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成功怀孕涉及不同的母体生理变化,胎儿和母体之间通过细胞因子、血管生成介质和激素的某些复杂相互作用,形成母胎免疫耐受,维持正常的妊娠状态。目前普遍认为,不明原因复发性流产与母胎界面免疫稳态平衡紊乱有关,与免疫机制之间存在显著关系。本文通过综述免疫稳态平衡紊乱在不明原因复发性流产中可能起到的作用,以期为临床治疗提供理论依据。
Research progress on immune homeostasis balance and treatment of unexplained recurrent miscarriage
Successful pregnancy involves different physiological changes in the mother,and the complex interac-tions between the fetus and mother through cytokines,angiogenic mediators,and hormones form maternal fetal im-mune tolerance and maintain a normal pregnancy state.At present,it is widely believed that unexplained recurrent miscarriage is related to the imbalance of immune homeostasis at the maternal fetal interface,and there is a signifi-cant relationship between it and immune mechanisms.This article reviews the possible role of immune homeostasis imbalance in unexplained recurrent miscarriage,in order to provide theoretical basis for clinical treatment.

Unexplained recurrent miscarriageImmune homeostasisDisorder

许烨烨、任丽萍

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上海市长宁区妇幼保健院妇产科,上海 200050

不明原因复发性流产 免疫稳态 紊乱

2025

贵州医药
贵州省医药卫生学会办公室

贵州医药

影响因子:0.493
ISSN:1000-744X
年,卷(期):2025.49(1)