儿童动脉导管未闭介入封堵相关并发症研究进展
Advances in the complications related to transcatheter closure of patent ductus arteriosus in children
程延超 1姜殿东 2韩波1
作者信息
- 1. 山东大学齐鲁医学院,济南 250021;山东省立医院小儿心脏科,济南 250021
- 2. 山东省立医院小儿心脏科,济南 250021
- 折叠
摘要
动脉导管未闭(patent ductus arteriosus,PDA)是儿童时期常见的先天性心脏病,发病率约为0.5％,占所有先天性心脏病的5％～10％.动脉导管的持续开放会影响儿童生长发育,增加罹患肺炎、感染性心内膜炎、新生儿坏死性小肠结肠炎等疾病的风险.相较于传统外科开胸手术,经皮介入封堵治疗儿童PDA的手术成功率高,住院时间短.经皮介入封堵已替代外科手术成为儿童PDA的首选治疗方式,但不能忽视介入封堵术后瓣膜反流、溶血、血小板减少、封堵器脱落或移位等相关并发症.该文对PDA介入封堵相关并发症的发生机制及处理方式进行综述,以期提高医生对相关并发症的认识,减少相关并发症的发生,改善患儿预后.
Abstract
Patent ductus arteriosus(PDA)is one of the most common congenital heart diseases in childhood.The prevalence of PDA is about 0.5％and PDA accounts for 5％-10％of congenital heart diseases.Continuous opening of the ductus arteriosus can affect children's growth and development.Meanwhile,PDA increases the possibility of pneumonia,infective endocarditis,neonatal necrotizing enterocolitis,and other diseases.Compared with traditional surgery,percutaneous interventional closure of PDA in children has a higher surgical success rate and shorter hospital stay.Clinical practice has proved that percutaneous interventional closure is the preferred method for children with PDA.However,transcatheter closure also has complications,including displacement,valvular regurgitation,hemolysis and thrombocytopenia.The review aims to illustrate the mechanism and treatment of the complications after PDA interventional closure,in order to increase the physician's awareness of those complications,reduce the incidence of the complications and improve the prognosis of the patients.
关键词
儿童/动脉导管未闭/介入封堵/并发症/3D打印Key words
Children/Patent ductus arteriosus/Transcatheter closure/Complication/3D printing引用本文复制引用
基金项目
山东省医药卫生科技发展计划项目(202106919782)
出版年
2024
NETL
NSTL
万方数据