Advances in cardiovascular diseases in children with Turner syndrome
Turner syndrome(TS),a condition among females with a karyotype containing one X chromosome and complete or partial absence of the second sex chromosome,affects 20～50 in 100 000 newborn girls.Congenital or acquired cardiovascular diseases are present in about half of patients with TS.The congenital defects occur in about 25％～50％of TS patients;aortic dilatation as an important risk factor for aortic dissection is common in adult patients with TS.Furthermore,arrhythmias are found more frequently in patients with TS.A higher prevalence of hypertension in children and adolescents with TS has also been reported,and the application of 24h ambulatory blood pressure monitoring may facilitates the diagnosis of hypertension among these children and adolescent.Thus,active health education,correct follow-up and timely intervention are crucially needed.
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