摘要
儿童睡眠健康贯穿儿童的生长发育全程,具有重要意义.睡眠障碍是影响儿童生长发育及成长健康的重要问题之一.存在睡眠障碍的儿童患病人数呈逐年上升趋势.目前研究表明儿童睡眠稳态受到干扰时通常伴随着神经内分泌系统活动的增加、免疫系统的激活、代谢紊乱等,导致相应激素(如皮质醇)、炎症细胞因子、代谢物质等稳态发生变化,相互影响,形成恶性循环.此外,遗传因素与睡眠的关系也越来越受关注.该文综述儿童睡眠健康和睡眠障碍机制、影响因素及研究进展,为临床干预儿童睡眠问题提供参考依据.
Abstract
Children's sleep health runs through the entire process of children's growth and development and is of great significance.Sleep disorders are one of the important problems affecting children's grow,development and growth health.The number of pediatric patients with sleep disorders is on the rise year by year.Current studies show that the disturbance of children's sleep homeostasis is usually accompanied by the increase of neuroendocrine system activities,the activation of immune system,metabolic disorders,etc,lead to the corresponding hormones(such as cortisol),inflammatory factors,metabolic substances and other homeostasis changes,mutual influence,forming a vicious cycle.In addition,the relationship between genetic factors and sleep is also increasingly concerned.This article reviews the mechanisms,influencing factors and research progress of children's sleep health and sleep disorders,aiming to provide a reference for clinical intervention in children's sleep problems.
基金项目
内蒙古自治区卫生健康委自治区卫生健康科技计划(202201046)
NETL
NSTL
万方数据