Progress on peripheral blood biomarkers in children with bronchial asthma
Bronchial asthma is one of the common chronic respiratory diseases in children,mainly manifested as airway hyperresponsiveness and chronic airway inflammation.The disease varies in phenotype,clinical presentation,course and response to treatment.Therefore,more precise and accessible biomarkers are needed for diagnosis and evaluation.Clinical assay of peripheral blood biomarkers only requires blood samples to be collected,can be repeatedly extracted and easily quantified,and are expected to improve the efficiency of asthma diagnosis and treatment,becoming a choice for clinical diagnosis and treatment.This article reviews the research progress of peripheral blood biomarkers in identifying the phenotype of childhood asthma,evaluating the severity,and predicting the therapeutic effect in recent years,with the aim to provide personalized medical strategies for children with asthma.