摘要
新生儿低血糖是一种临床常见的糖代谢疾病,尤其易发生于早产儿.反复持续的低血糖可导致早产儿出现永久性神经损伤或死亡等不良结局,严重影响患儿预后.研究认为孕母妊娠期疾病、妊娠期用药、早产儿的各种病理生理状态均可增加早产儿低血糖的发病率.该文综合了近年来国内外相关文献,就目前早产儿低血糖的病理生理机制、危险因素、诊断、预防与治疗进行综述,以期早发现、早诊断、早治疗,降低低血糖的发病率.
Abstract
Neonatal hypoglycemia,a common disorder of abnormal glucose metabolism,occurs especially in preterm newborns.Hypoglycemia that occurs frequently and persistently may result in severe consequences for premature infants,including death or permanent brain damage.In recent years,an increasing number of research findings have demonstrated that the following conditions have been linked to an increased risk of hypoglycemia in preterm infants:maternal sickness during pregnancy,pharmaceutical use during pregnancy,and various pathophysiological states of the preterm infant.This review summarizes the current pathophysiological mechanism,risk factors,diagnosis,prevention,and treatment of hypoglycemia in preterm newborns through analyzing the pertinent literature that has been published recently both domestically and internationally,with the aim of early detection,early diagnosis and early treatment,and reducing the incidence of hypoglycemia.
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