Progress on correlation between Guillain-Barré syndrome spectrum diseases and anti-glycolipid antibodies in children
Guillain-Barré syndrome(GBS)is a class of immune-mediated acute inflammatory peripheral neuropathy.With the in-depth understanding of its phenotype,a spectrum disease including classic GBS and variant GBS has been gradually formed.A number of studies at home and abroad have found that anti-peripheral nerve membrane surface glucolipid antibodies,including anti-ganglioside antibodies and anti-Sulfatide antibodies,are closely related to GBS spectrum diseases.As a part of peripheral nerve antibodies,anti-glycolipid antibodies play an important role in the diagnosis,clinical classification,disease assessment and prognostic assessment of GBS spectrum diseases.The article reviews the progress on the correlation between anti-glycolipid antibody and GBS spectrum disease in children,in order to provide clinical reference.
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