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儿童肝母细胞瘤的诊治研究进展

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肝母细胞瘤(hepatoblastoma,HB)是儿童期最常见的肝脏恶性肿瘤,患儿的主要临床表现为腹部包块,约半数患儿初诊时肿瘤不能被完整切除.手术治疗联合化疗可以显著提高HB患儿的远期存活率,已经成为HB的重要治疗方案,尤其是术前临床分期、病理类型、化疗方案和手术方式的选择对于HB的治疗具有重要意义.该文就儿童HB的诊断和治疗的研究进展进行综述,以期为临床治疗提供参考.
Progress on the diagnosis and treatment of hepatoblastoma in children
Hepatoblastoma is the most common malignant tumor of the liver in childhood.The main clinical symptom of children is abdominal mass,and half of them are unable to completely be resected at initial diagnosis.In recent years,surgical treatment combined with chemotherapy can significantly improve the long-term survival rate of hepatoblastoma,and it has become the important treatment plan for hepatoblastoma.Especially the preoperative clinical staging,pathological types,chemotherapy,and surgery are important for the treatment of hepatoblastoma.This article reviews the latest research progress on the diagnosis and treatment of childhood hepatoblastoma in order to provide the help for clinical treatment.

ChildrenHepatoblastomaPathologyTreatment

刘信、田野、李庆庆

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辽宁省肿瘤医院 中国医科大学肿瘤医院结直肠外科,沈阳 110044

辽宁省肿瘤医院 中国医科大学肿瘤医院内镜科,沈阳 110044

儿童 肝母细胞瘤 病理 治疗

辽宁省自然科学基金

2020-MS-060

2024

国际儿科学杂志
中华医学会,中国医科大学

国际儿科学杂志

CSTPCD
影响因子:1.057
ISSN:1673-4408
年,卷(期):2024.51(6)
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