Progress on the regulation of gastrointestinal motility by gut microbiota and their metabolites
There are the largest and most complex microbial groups in the human gastrointestinal tract,which constantly adapt to the host environment and provide multiple key functions for the host.Currently,many diseases are closely related to gastrointestinal motility disorders,including diarrhea,constipation,irritable bowel syndrome and so on.Increasing evidence indicates that the gut microbiota and their metabolites are able to influence gastrointestinal motility,which subsequently influences the development of diseases,and the relationship between them has become a research topic.This article reviews the mechanisms of gut microbiota and their metabolites as well as the mechanisms of probiotics in regulating gastrointestinal motility,in an attempt to provide valuable clues for developing therapies that rely on gut microbiota to improve gastrointestinal motility.
Gut microbiotaGastrointestinal motilityIntestinal nervous systemIntestinal smooth muscleMetabolites
NETL
NSTL
万方数据
