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新生儿血小板输注的临床研究进展

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血小板输注是临床治疗新生儿血小板减少症和预防早产儿出血性疾病的重要干预措施之一,临床输注率高,然而其在临床应用中仍存在一些争议.血小板输注除了要考虑血小板计数,还要评估血小板减少的病因及是否存在出血倾向,并应考虑血小板对其他系统疾病的影响.临床医师常常需要在患儿危重状态下快速决定是否输注血小板.该文从与临床实践密切相关的问题进行总结,旨在梳理新生儿血小板输注的临床研究进展,为临床医生进行输血决策时提供参考,也为未来临床研究提供方向.
Progress of clinical research on neonatal platelet transfusion
Platelet transfusion is one of the critical clinical therapies of neonatal thrombocytopenia and significant preventive measures of bleeding diseases in preterm infants.The platelet transfusion rate is high in clinical practice,whereas some controversies emerge in its clinical application.Platelet transfusion decision-making should take into account the platelet count and the causes of thrombocytopenia.In addition,the presence of bleeding tendency and platelet effects on other systemic disorders should be considered.Clinicians often need to make rapid decisions about whether to transfuse platelets in a critically situation.On the basis of the comprehensive overview of issues that are closely pertinent to the field of clinical practice,this article is dedicated to elucidate the advancements in clinical research pertaining to neonatal platelet transfusions,aiming to serve as a reference for clinicians when making transfusion decisions and to chart a course for future clinical investigations.

NeonatePreterm infantThrombocytopeniaPlatelet transfusion

谢甜甜、雷宏涛、王文华、赵璞、张勤

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西安医学院 710021

陕西省人民医院新生儿科,西安 710068

新生儿 早产儿 血小板减少症 血小板输注

陕西省自然科学基金青年项目

2021JQ-915

2024

国际儿科学杂志
中华医学会,中国医科大学

国际儿科学杂志

CSTPCD
影响因子:1.057
ISSN:1673-4408
年,卷(期):2024.51(8)