ATP-binding cassette subfamily C member 4(ABCC4),a member of ATP-binding cassette transporter C subfamily,is involved in extracellular signaling pathways and cellular protection.As a multifunctional transporter protein,ABCC4 is prevalently present in multiple cells of the human body,and is capable of pumping out a variety of endogenous and exogenous substances from cells.It is closely related to the occurrence and development of multifarious diseases,and is also a potential therapeutic target for many diseases.The structure,function and related research progress of ABCC4 in a large amount of systemic diseases are reviewed.
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