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母乳低聚糖与婴儿健康的研究进展

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母乳低聚糖(human milk oligosaccharides,HMOs)是母乳中特有的碳水化合物,在哺乳早期的母乳中含量丰富,对婴儿的生长发育起关键作用.HMOs可作为肠道细胞反应调节剂、抗黏附的抗菌剂、免疫调节剂以及提供益生元效应.HMOs在调节肠黏膜屏障功能、抗感染以及促进免疫功能发育与成熟等方面发挥了重要作用,对婴儿近远期健康和降低某些疾病的发生风险产生深远影响.该文就HMOs对婴儿健康的影响进行综述.
Progress on human milk oligosaccharides and infants health
Human milk oligosaccharides(HMOs)are the unique carbohydrates in breast milk,which are abundant in early lactation,and play a key role in infant growth and development.HMOs can be used as response regulators of intestinal cells,anti-adhesion antibacterial agents,immunomodulatory agents,and provide prebiotic effects.HMOs play an important role in regulating intestinal mucosal barrier function,anti-infection,and promoting the development and maturation of immune function,which have a profound impact on the short-term and long-term health of infant and reducing the risk of certain diseases.This article reviews the impact of HMOs on infant health.

InfantHuman milk oligosaccharidesGut microbiotaImmunity

牛彦、李兆娜、刘尊杰、寇晨

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首都医科大学附属北京妇产医院 北京妇幼保健院新生儿科 100026

婴儿 母乳低聚糖 肠道菌群 免疫

2024

国际儿科学杂志
中华医学会,中国医科大学

国际儿科学杂志

CSTPCD
影响因子:1.057
ISSN:1673-4408
年,卷(期):2024.51(12)