首页|胎儿宫内及出生后生长轨迹研究进展

胎儿宫内及出生后生长轨迹研究进展

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胎儿出生体重是妊娠结束时评估胎儿生长状况的最直观指标,但其作为一个单一的衡量指标并不能反映整个妊娠期胎儿生长的动态变化,相似的出生体重可能沿着不同的生长轨迹获得。目前胎儿生长受限或巨大儿等诊断是基于估计胎儿体重或腹围的横断面临界值判断的,而横断面测量可能会遗漏某些未能达到其潜能、但仍高于传统临界值的胎儿亚组,这些亚组的胎儿同样面临不良围产结局的风险。对胎儿生长进行纵向评估可能是解决这一临床问题的有效方法之一。本文从胎儿宫内及出生后生长轨迹的影响因素、不同轨迹下胎儿的远期健康结局等方面进行综述,以期为相关领域的进一步研究提供参考。
Research progress of fetal growth trajectories in utero and after birth
Fetal birth weight is the most intuitive indicator to evaluate fetal growth status at the end of pregnancy,but as a single measure,it cannot reflect the dynamic changes in fetal growth throughout the entire pregnancy.Similar birth weights may be achieved along different growth trajectories.At present,the diagnosis of fetal growth restriction or macrosomia is based on cross-sectional threshold values of estimated fetal weight or abdominal circumference,which may overlook certain subgroups of fetuses that do not reach their potential but still exceed traditional threshold values.Fetuses in these subgroups also face the risk of adverse perinatal outcomes.Longitudinal assessment of fetal growth may be one of the effective ways to address this clinical problem.This article provides a comprehensive review of factors influencing the fetal growth trajectories both in utero and after birth,as well as the long-term health outcomes of fetuses on different trajectories,so as to provide reference for further research in the field of related.

fetal growth trajectoryintrauterine developmenthealthy early in lifegrowth and developmentmodel

王亚新、马良坤、孙崟、高劲松、刘娜娜、杨萱瑾

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国家妇产疾病临床医学研究中心 中国医学科学院北京协和医学院 北京协和医院妇产科,北京 100730

胎儿生长轨迹 宫内发育 生命早期健康 生长发育 模型

国家重点研发计划妊娠期糖尿病妇女体重增长推荐值标准项目中央级公益性科研院所基本科研业务费专项中国医科院临床与转化医学研究基金中国医科院医学与健康科技创新工程项目中国医科院医学与健康科技创新工程项目

2022YFC2703304201919012019XK3200072020-I2M-2-0092021-I2M-1-023

2024

中国妇幼健康研究
西安交通大学,中国疾病控制中心妇幼保健中心

中国妇幼健康研究

CSTPCD
影响因子:0.942
ISSN:1673-5293
年,卷(期):2024.35(3)
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