The Effect of Microplastics Exposure on Female and Their Offspring Health
Microplastics(MPs)refer to plastics with a diameter of less than 5 mm.As a new environmental pollutant,MPs can enter the body through the respiratory tract,digestive tract and skin,and then deposit in multiple tissues such as the intestine,liver and ovary.MPs exposure has toxic effects on the female reproductive system by affecting follicle development,oocyte quality and sex hormone levels through apoptosis,oxidative stress and disorders of hypothalamic-pituitary-gonadal axis,thereby reducing female fertility.Moreover,recent studies have found that MPs can enter the placenta and lead to the abnormal placental metabolism,immune imbalance at the maternal and fetal interface,and the impaired placental structure.MPs can further enter the offspring through the placental barrier after maternal exposure to MPs,causing adverse effects on the neural,digestive,reproductive and other multiple systems of the offspring.Given the toxicity of MPs and the persistence in environment,the exposure to MPs should be reduced in daily life to prevent human from the harm of MPs.
MicroplasticsEnvironmental exposureOvarian follicleGrowth and developmentFertilityReproductive health
万方数据
维普
