HPV经精子传播及其对早期胚胎发育的影响
HPV Transmission through Sperm and Its Impact on Early Embryonic Development
赵安琪 1刘霖 1谭小方2
作者信息
- 1. 226001 南通大学医学院
- 2. 南通大学附属南通妇幼保健院生殖医学中心
- 折叠
摘要
人乳头瘤病毒(human papilloma viruis,HPV)感染是全球常见的性传播疾病之一,与多种器官的肿瘤发生有关.近年来,HPV经生殖细胞传播及其对早期胚胎发育的潜在影响备受关注.研究表明,HPV感染可能影响男性精子质量,导致不育,同时可能干扰胚胎发育,增加自然流产的风险,并对辅助生殖技术的妊娠结局产生不良影响.综述HPV经精子传播及其对早期胚胎发育影响的研究进展,旨在深入理解HPV对生育健康的潜在威胁,并为临床实践和进一步研究提供参考.
Abstract
Human papilloma virus(HPV)infection is one of the most common sexually transmitted diseases,which is associated with the development of tumors in multiple organs.In recent years,the impact of HPV infection on fertility has garnered significant attention,particularly its vertical transmission through germ cells and potential effects on early embryonic development.Studies have shown that HPV infection may affect sperm quality,leading to infertility,and may also interfere with embryonic development,increasing the risk of spontaneous abortion and adversely affecting pregnancy outcomes in assisted reproductive technology.This review summarizes the research progress on the vertical transmission of HPV through sperm cells and its impact on early embryonic development,to deeply understand the potential threat of HPV to reproductive health and to provide references for clinical practice and further research.
关键词
精子/胚胎发育/流产,自然/生殖技术,辅助/传染性疾病传播,垂直/人乳头瘤病毒Key words
Spermatozoa/Embryonic development/Abortion,spontaneous/Reproductive techniques,assisted/Infectious disease transmission,vertical/Human papilloma virus引用本文复制引用
基金项目
江苏卫生创新团队项目()
南通大学临床医学专项项目(2022LY014)
出版年
2024
国家科技期刊平台
NSTL
万方数据